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Restylane® Refyne 1 Syringe

Natural Results That Refyne Your Laugh Lines. A next-generation hyaluronic acid dermal filler designed to help support your skin while keeping you looking like you.

Description

Restylane® Refyne is designed with XpresHAn Technology™ to help soften laugh lines (nasolabial folds and marionette lines). This can help you restore a more natural look to your face while maintaining your facial expressions. So, you always look like you. Talk to your specialist and see for yourself why it’s worth it.

As skin loses elasticity with age, the lines that run from the sides of your nose toward the corners of your mouth (nasolabial folds) and the lines that run from the corners of your mouth toward the chin (marionette lines) appear more noticeable. Restylane Refyne is a specifically formulated hyaluronic acid dermal filler made with XpresHAn Technology™ that helps correct these lines for a more natural look to your face. The unique cross-linking of the gel in Restylane Refyne is also designed to help support your natural expression—for real-life results that help maintain natural movement when you're smiling, frowning, and even puckering up.

Additional Info

More Information
Benefits	Restylane Refyne temporarily reduces signs of aging on your face by smoothing the wrinkles and folds that form around your nose and extending down to the corners of your mouth (laugh lines). This natural, smooth look should last for up to 12 months. Restylane Refyne was studied in many patients like yourself to determine if it was effective in treating laugh lines and to ensure that it is safe for use. The study doctors reported: • 79% of patients had at least a 1-point improvement in wrinkle appearance 6 months after treatment • 62% of patients had at least a 1-point improvement in wrinkle appearance 1 year after treatment The patients reported: • 79% rated an improvement in the appearance of their wrinkles 6 months after treatment • 67% rated an improvement in the appearance of their wrinkles 1 year after treatment
FAQs	What is Restylane Refyne? Restylane Refyne is a dermal filler injected under the (facial) skin. Once in place, it helps smooth away your “laugh lines” – the wrinkles and folds that may form at the sides of your nose and run down toward the corners of your mouth. Restylane Refyne is made out of hyaluronic acid - a naturally occurring sugar, found in the body that gives the skin moisture, volume, and elasticity – and a small amount of lidocaine, which is a commonly used local anesthetic to numb the skin. Restylane Refyne is made using a manufacturing process called XpresHAn Technology™, which creates a smooth, injectable gel that can give your skin a natural, soft look What is Restylane Refyne for? As you age, your facial skin begins to lose its elasticity and volume. As a result, your “laugh lines”, the creases that run from the sides of your nose toward the corners of your mouth, become more pronounced. Restylane Refyne injectable gel is designed to temporarily help counter this by smoothing out these wrinkles and folds and restoring a natural, soft look to your face. Restylane Refyne has been shown to maintain this effect for up to 12 months. Are there any reasons why I should not receive Restylane Refyne? Before using Restylane Refyne, your doctor will talk to you about your medical history to determine if you are an appropriate candidate for treatment. You will be asked questions about possible allergies to ensure that Restylane Refyne can be safely administered. Tell your doctor about all of your medical conditions, including if you: • Have severe allergies with a history of severe reactions (anaphylaxis). Use of Restylane Refyne may result in an allergic reaction. • Are allergic to the anesthetic lidocaine or to any of the proteins used to make the hyaluronic acid in Restylane Refyne (bacterial proteins). Use may result in an allergic reaction. What side effects were seen in the clinical study? In the study of Restylane Refyne, most patients reported the following side effects at the site where they received the injection: • Swelling • Bruising • Lumps/Bump Formation • Pain/Tenderness • Itching • Redness Most patients said their side effects were mild, short-lived, and did not require them to call their doctor. These patients said that their side effects disappeared within 1-2 weeks. Patients also reported that the anesthetic lidocaine, which is part of the Restylane Refyne injection and used to numb the injection site, significantly reduced pain during and after their procedure.
Treatment Type	Filler
Treatment Problem or Condition	Perioral Lines
Brand	Restylane

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Usage

Restylane Refyne is indicated for injection into the mid-to-deep dermis for correction of moderate to severe facial wrinkles and folds (such as nasolabial folds) in patients over the age of 21.

Ingredients

Restylane® Refyne is a sterile, biodegradable, viscoelastic, non-pyrogenic, clear, colorless, and homogeneous soft hyaluronic acid gel with a moderate lifting capacity. The product has a sodium hyaluronate concentration of 20 mg/mL in phosphate-buffered saline at pH 7 and contains 3 mg/mL lidocaine hydrochloride.