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Restylane® Defyne 1 Syringe

Defyne your look from every angle. Crafted with XpresHAn Technology™, Restylane® Defyne helps smooth out deep laugh lines (nasolabial folds and marionette lines) as well as enhance chin projection. Using innovative cross-linking technology, Restylane Defyne is a hyaluronic acid dermal filler that can help restore a more youthful, natural-looking appearance, while helping you maintain your natural expressions and movement.

Description

Restylane® Defyne is a dermal filler injected under the (facial) skin. Once in place, it helps smooth away your “laugh lines” – the wrinkles and folds that may form at the sides of your nose and run down toward the corners of your mouth. Restylane® Defyne may also be used to improve the profile, shape, and size of your chin.

Restylane® Defyne is made out of hyaluronic acid - a naturally occurring sugar, found in the body that gives the skin moisture, volume, and elasticity – and a small amount of lidocaine, which is a commonly used local anesthetic to numb the skin. The hyaluronic acid is crosslinked with BDDE, an ingredient that helps form a network of hyaluronic acid to provide a gel filler that lasts longer. Hyaluronic acid fillers, including Restylane® Defyne, contain hyaluronic acid that has been modified to last longer in the body than the naturally occurring hyaluronic acid.

As we age, our skin loses elasticity. This causes the lines that run along the side of the face and mouth (nasolabial folds and marionette lines) to become more pronounced as well as the chin to recede so far back toward the neck that it creates an imbalance of facial features (chin retrusion). Restylane Defyne is crafted with XpresHAn Technology™ to correct these deepened lines and wrinkles and improve chin projection by correcting mild-to-moderate chin retrusion. The unique cross-linking of the gel in Restylane Defyne is also designed to help support your facial expressions—for natural-looking results that help maintain your natural movement.

Additional Info

More Information
Benefits	Restylane® Defyne temporarily reduces signs of aging on your face by smoothing the wrinkles and folds that form around your nose and extending down to the corners of your mouth (laugh lines). This natural, smooth look should last for up to 12 months. Restylane® Defyne was studied in many patients like yourself to determine if it was effective in treating laugh lines and to ensure that it is safe for use. The study doctors reported: • 77% of patients had at least a 1-point improvement in wrinkle appearance 6 months after treatment. • 70% of patients had at least a 1-point improvement in wrinkle appearance 1 year after treatment. The patients reported: • 78% rated an improvement in the appearance of their wrinkles 6 months after treatment. • 64% rated an improvement in the appearance of their wrinkles 1 year after treatment.
FAQs	What is Restylane® Defyne for? As you age, your facial skin begins to lose its elasticity and volume. As a result, your “laugh lines”, the creases that run from the sides of your nose toward the corners of your mouth, become more pronounced. Restylane® Defyne injectable gel is designed to temporarily help counter this by smoothing out these wrinkles and folds and restoring a natural, soft look to your face. Restylane® Defyne may also be used for augmentation of the chin region to improve the chin profile in patients with mild to moderate chin retrusion over the age of 21. This means it may be used in the chin area to improve the profile, shape, and size of your chin. Restylane® Defyne has been shown to maintain this effect for up to 12 months. Are there any reasons why I should not receive Restylane® Defyne? Before using Restylane® Defyne, your doctor will talk to you about your medical history, to determine if you are an appropriate candidate for treatment. You will be asked questions about possible allergies to ensure that Restylane® Defyne can be safely administered. Tell your doctor about all your medical conditions, including if you: • Have severe allergies with a history of severe reactions (anaphylaxis). Use of Restylane® Defyne may result in an allergic reaction. • Are allergic to the anesthetic lidocaine or to any of the proteins used to make the hyaluronic acid in Restylane® Defyne (bacterial proteins). Use may result in an allergic reaction. What side effects were seen in the clinical studies? In the study of Restylane® Defyne for correction of wrinkles and folds that form around your nose and extend down to the corners of your mouth (laugh lines), most patients reported the following side effects at the site where they received the injection: • Swelling • Lumps/Bump Formation • Redness • Pain/Tenderness • Bruising • Itching Most patients said their side effects were mild, short-lived, and did not require them to call their doctor. These patients said that their side effects disappeared within 1-2 weeks. Patients also reported that the anesthetic lidocaine, which is part of the Restylane® Defyne injection and used to numb the injection site, significantly reduced pain during and after their procedure.
Treatment Type	Filler
Treatment Problem or Condition	Facial Folds, Facial Volume Loss, Fine Lines, Wrinkles
Brand	Restylane

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Usage

Restylane® Defyne is injected into the facial skin through a small needle to smooth facial wrinkles and folds (laugh lines), resulting in a more youthful appearance of the skin. Restylane® Defyne may also be injected into your chin to improve the profile, shape, and size of your chin. For most patients, the procedure only takes 15 – 30 minutes.

Ingredients

Restylane® Defyne is made out of hyaluronic acid - a naturally occurring sugar, found in the body that gives the skin moisture, volume, and elasticity – and a small amount of lidocaine, which is a commonly used local anesthetic to numb the skin. The hyaluronic acid is crosslinked with BDDE, an ingredient that helps form a network of hyaluronic acid to provide a gel filler that lasts longer. Hyaluronic acid fillers, including Restylane® Defyne, contains hyaluronic acid that has been modified to last longer in the body than the naturally occurring hyaluronic acid