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Letybo® 100 Units - 1 Vial
Letybo® 100 Units - 1 Vial

Letybo® 100 Units - 1 Vial

Letybo® 100 Unit vial is a prescription medication containing letibotulinumtoxinA-wlbg, a purified botulinum toxin type A. It is used to temporarily improve the appearance of moderate to severe glabellar lines (frown lines between the eyebrows) in adults. Each single-dose vial contains 100 units of freeze-dried powder, which should be reconstituted with sterile, preservative-free 0.9% sodium chloride solution before intramuscular injection. A common dilution is 2.5 mL per 100 units, resulting in a concentration of 4 units per 0.1 mL. Letybo works by inhibiting the release of acetylcholine at the neuromuscular junction, leading to temporary muscle relaxation and smoothing of wrinkles. The effects typically become noticeable within a few days and can last up to three months. Approved by the FDA in February 2024, Letybo is available in 100-unit vials and should be stored refrigerated between 2°C to 8°C (36°F to 46°F) in its original packaging to protect from light.

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Letybo® 100 Unit Vial (letibotulinumtoxinA-wlbg) is a prescription injectable neuromodulator designed to temporarily improve the appearance of moderate to severe glabellar lines—commonly known as frown lines—between the eyebrows in adult patients. Approved by the FDA in 2024, Letybo® is the latest botulinum toxin type A product to enter the U.S. aesthetics market, offering a safe and effective alternative to other well-known brands like Botox®, Dysport®, and Xeomin®. Each single-use vial contains 100 units of a purified botulinum toxin type A complex, presented as a lyophilized (freeze-dried) powder. Before administration, the product must be reconstituted with sterile, preservative-free 0.9% sodium chloride (saline) to the desired concentration—most commonly 2.5 mL per vial, yielding a dilution of 4 units per 0.1 mL. Once reconstituted, Letybo® is injected intramuscularly into specific facial muscles to produce temporary muscle relaxation, effectively smoothing dynamic wrinkles caused by repetitive facial movements. Letybo® functions by blocking the release of acetylcholine at the neuromuscular junction, which inhibits muscle contractions. Clinical effects typically begin to appear within 2 to 3 days after injection, with full results visible by 7 to 14 days. The aesthetic improvements can last for approximately 3 to 4 months, though individual results may vary depending on dosage, injection technique, and patient factors. Manufactured under strict quality standards, Letybo® must be stored refrigerated between 2°C to 8°C (36°F to 46°F) and protected from light in its original packaging. It is suitable for use by licensed healthcare professionals trained in facial anatomy and botulinum toxin injection techniques. As a growing favorite among aesthetic practitioners, Letybo® combines proven clinical efficacy with high patient satisfaction, making it an excellent choice for practices looking to expand their neuromodulator offerings.

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Benefits
  • FDA-Approved for Safety and Efficacy - Letybo is FDA-approved (as of 2024) for the treatment of moderate to severe glabellar lines, offering peace of mind to both practitioners and patients.
  • Smooths Frown Lines - Effectively Targets and relaxes the muscles between the eyebrows to reduce the appearance of frown lines, creating a smoother, more youthful look.
  • Fast Onset of Results - Visible improvement typically begins within 2–3 days after treatment, with full results usually seen by day 7 to 14.
  • Long-Lasting Effects - A single treatment can provide aesthetic results for up to 3–4 months, reducing the frequency of injections required over time.
  • High Patient Satisfaction - Clinical trials and real-world use have shown high satisfaction rates due to natural-looking results and minimal downtime.
  • Purified Formulation - letybo contains a refined botulinum toxin type A complex, with a consistent potency profile, supporting reliable results.
  • Cost-Effective Alternative - As a newer entry to the market, letybo often comes at a competitive price point compared to legacy neurotoxin brands, helping providers manage costs while maintaining treatment quality.
  • Flexible Dilution & Application - Allows for customizable reconstitution and dosing strategies, offering injectors flexibility in tailoring treatments to each patient's needs.
  • Well-Tolerated with Minimal Downtime - Most patients experience little to no downtime, with mild and temporary side effects, making it a convenient “lunchtime” procedure.
FAQs

1. What is letybo?
letybo® is a botulinum toxin type A injectable used to temporarily reduce the appearance of moderate to severe frown lines (glabellar lines) between the eyebrows in adults. It works by relaxing specific facial muscles.

2. How is letybo different from other neurotoxins like Botox® or Dysport®?
letybo offers similar clinical efficacy, onset, and duration of results. As a newer FDA-approved product, it is competitively priced and has shown consistent, natural-looking outcomes in studies. It is manufactured with high purity standards.

3. When will I see results?
Initial results are typically noticeable within 2 to 3 days, with full results usually visible by day 7 to 14 post-injection.

4. How long do the effects of letybo last?
Results generally last about 3 to 4 months. Individual factors like metabolism, muscle activity, and dosage can influence how long the effects last.

5. Is the treatment painful?
Most patients experience minimal discomfort. The injections are quick and use a very fine needle. A topical numbing agent can be applied if desired.

6. Is there any downtime after receiving letybo?
There is little to no downtime. Most patients return to normal activities immediately after treatment. Mild redness or swelling at the injection site may occur and typically resolves quickly.

7. Who is a good candidate for letybo?
Healthy adults who wish to reduce dynamic wrinkles (caused by muscle movement) are ideal candidates. Pregnant or breastfeeding individuals and those with certain neurological conditions should avoid treatment.

8. How should letybo be stored?
Before reconstitution, it must be stored refrigerated at 2°C to 8°C (36°F to 46°F) and protected from light. After reconstitution, it should be used within a few hours as directed by clinical guidelines.

9. Can I combine letybo with other treatments?
Yes, letybo is commonly combined with dermal fillers, skincare treatments, and laser procedures as part of a comprehensive aesthetic plan. Always consult your provider.

10. Are there any side effects?
Possible side effects include temporary bruising, swelling, or mild headache. Rare but serious side effects include eyelid drooping or allergic reaction. Always seek treatment from a qualified provider.

Treatment Problem or Condition Fine Lines, Wrinkles
Brand Letybo®

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Glabellar Lines (Frown Lines) - Primary FDA-approved indication Targets the vertical lines between the eyebrows caused by repeated muscle movement (corrugator and procerus muscles)
Forehead Lines (Frontalis Lines) - Off-label use by trained professionals
Helps reduce horizontal forehead wrinkles for a smoother upper face
Crow’s Feet (Lateral Canthal Lines) - Softens lines at the outer corners of the eyes caused by smiling or squinting
Brow Lift - Subtle lift of the eyebrows for a more refreshed and open appearance
Bunny Lines (Nasal Lines) - Smooths fine wrinkles on the sides of the nose from scrunching
Perioral Lines (Smoker’s Lines) - Reduces fine vertical lines around the lips, enhancing lip definition
Dimpled Chin (Mentalis Muscle) - Softens chin dimpling or “pebble chin” for a smoother contour
Jawline Slimming (Masseter Reduction) - Reduces the size of the masseter muscles for facial slimming and relief from teeth grinding (bruxism)
Neck Bands (Platysmal Bands) - Softens visible vertical neck lines for a more youthful neckline
Hyperhidrosis (Excessive Sweating) - Off-label use for underarms, palms, or soles to reduce excessive sweating by blocking sweat gland activation

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